Propecia

What is it used for?

Propecia (finasteride) is used to stop and help prevent the hair loss according to male pattern (alopecia). Finasteride is also used to treat benign prostatic hyperplasia and excessive hair growth in transgender women. The drug is taken over an extended course of time in order for measurable health benefits to be presented, sometimes over the course of a lifetime.

Propecia contains finasteride. By placing an order for this drug at our website, you confirm that you are aware about the pharmacodynamics, method of application, safe doses and potential adverse events of the medication. Doctor’s opinion and dose appointment are required to start finasteride therapy. In case of serious or persistent side effects, seek medical help.

Drug description and mechanism

Propecia (finasteride, in New Zealand also available under the trademark names of Profal and ReGen) is an inhibitor II of alpha-reductase, acting at the level of prevention of testosterone degrading to dehydrotestosterone (DHT) in the scalp area, which prevents the hair bulbs from loosening and the eventual hair loss from weakening.

Be advised that the hair regrowth in the bald areas may or may not happen following the therapy; a slight increase was observed in 39.5% of Propecia users.

Doses and application method

Propecia contains 1mg of finasteride and is supposed to be taken in the amount of 1 tablet once a day, if not directed otherwise by your prescriber. Remember that the intake of Propecia should always follow a doctor consultation, and the dose should be appointed by a licensed healthcare specialist.

A tablet of Propecia is taken with a sufficient amount (1/2 to a full glass) of water without chewing or breaking. The drug can be taken with or without meals.

Note that in order for the meaningful benefits to be achieved, the therapy should last for several months, and in certain cases for a lifetime. If you discontinue Propecia, the reversal of achieved effects can be expected within a year.

Cautious use

Propecia is not intended for the use in female population. Finasteride has excellent capacity of getting absorbed through the skin, and therefore should not be handled by women without protecting gloves, especially in case of pregnancy of breastfeeding.

The benefits of Propecia use should be carefully evaluated in individuals with mild to moderate renal insufficiency.

Possible drug interactions

Tell your prescriber about every drug you are currently taking, prescription, over-the-counter, food supplement or herbal preparation. Propecia should be coadministered with drugs from the group of PDE5 inhibitors with caution, but no other clinically significant drug interactions have been reported for Propecia.

Propecia adverse experiences

Propecia can give mild to moderate side effects that can be felt during dosing and after withdrawal of finasteride. They are:

  • increased sensitivity of breasts, breast enlargement due to swelling
  • sexual dysfunction
  • decreased libido
  • decreased ejaculate volume
  • gynecomastia (0,5 vs 0,1% according to the PLESS study)
  • mammal carcinoma
  • swelling of the lips
  • rash
  • testicular sensitivity
  • depression
  • anxiety

In rare cases, patients taking Propecia have displayed suicidal ideology. If you find yourself depressed or absorbed in suicidal thoughts, immediately contact your prescriber or any other qualified therapist, and discontinue Propecia.

Propecia contraindications

Propecia is not intended for the use in women and can result in severe hormonal disruptions if administered to female population. Propecia is contraindicated in the following conditions:

  • pregnancy
  • breastfeeding
  • minor age
  • hypersensitivity towards finasteride, lactose or other drug components

Overdose

No side effects were observed in patients treated with single doses of finasteride up to 400 mg or doses up to 80 mg / day for three months. In case of overdose, stop finasteride therapy and proceed to symptomatic treatment.

Missed dose

In case of missing a dose of Propecia, take a pill as soon as you remember to if it has been less than 12 hours after your regular intake time. If it has been more than 12 hours after the regular time of Propecia dosing, skip the dose and take the next one as scheduled. Do not take two pills at once to make up for the missed dose. If uncertain of what to do, contact your pharmacist or prescriber for instructions. Missing a single dose of Propecia will not affect the results in the long run.

Nonclinical toxicology

In laboratory animals the administration of finasteride for long periods may cause decreased fertility. Also in humans the administration of finasteride can cause effects on male fertility or sperm count; in some patients a reduction in ejaculation volume has been observed.