What is it used for?
Levitra Super Force (vardenafil hydrochloride trihydrate, dapoxetine hydrochloride) is a multifunctional solution used to help male patients achieve penetrative hardness of erection and delay the ejaculatory time. The drug is appointed for the treatment of erectile dysfunction (ED) and premature ejaculation (PE).
Levitra Super Force contains two active components: vardenafil hydrochloride trihydrate and dapoxetine hydrochloride, each of them requiring medical appointment and dose titration based on individual findings following physical examination. By ordering the drug from our pharmacy, you confirm that you have consulted a licensed healthcare provider, and will rely on them in future in case of developing adverse reactions that require medical attention.
Drug mechanism explained
The mechanism of Levitra Super Force is based on the combination of two components vardenafil hydrochloride trihydrate and dapoxetine hydrochloride, one of which is an erectogenic vasodilator promoting healthy erections, the other is an antidepressant of SSRI class delaying ejaculation.
Vardenafil improves penile blood circulation by blocking phosphodiesterase type 5 (PDE5), releasing nitric oxide (NO) and favoring the build-up of the substance called cyclic guanosine monophosphate (cGMP) by preventing its conversion to guanosine triphosphate (GTP). cGMP is an essential part of the healthy erectile mechanism: it promotes vascular elasticity and allows blood flow freely into the erectile bodies lodged alongside the penile shaft and stay there until the moment of ejaculation. Vardenafil acts only in the presence of sexual stimuli.
Dapoxetine, a representative of the class of drugs called selective serotonin reuptake inhibitors, promotes accumulation of serotonin in the brain, which favors upkeep of erection for as long as it takes both partners to have a satisfactory sexual act. Using dapoxetine makes ejaculation more or less a volitional act. The exact mechanism behind dapoxetine effect is not yet studied.
The combination of vardenafil and dapoxetine is an approved and practical solution, as both conditions of erectile deficit and ejaculatory precocity are often coinciding and mutually aggravating among the male population of New Zealand.
Method and dosing
Levitra Super Force comes in the dose of vardenafil 20mg and dapoxetine 60mg. Those doses are maximal recommended amounts of both substances, so caution should be taken when the drug is administered for the first time and to patients with decreased rate of creatinine clearance.
Take a tablet of Levitra Super Force 60 minutes in anticipation to sexual activity. Wash down with half a glass or a full glass of water, without breaking the pill in your mouth, or crushing it and adding to foods or drinks.
Use with caution
Levitra Super Force should be used with extreme caution in persons with:
- compromised function of kidneys
- compromised function of liver
- history of mental disorders (depression, mania)
If you cannot engage in physical activity because problems with the heart, do not take Levitra Super Force.
Levitra Super Force has a potential of forming addiction, and should not be used in individuals with the history of addictions.
Discontinuation of Levitra Super Force therapy should be done under professional supervision.
Contraindications for administration
The use of Levitra Super Force in certain populations is contraindicated. Conditions that are not compatible with vardenafil / dapoxetine therapy are:
- heart disease, including recently experienced stroke
- advanced stages of kidney or liver disease
- diseases of eye retina, NAION or closed-angle glaucoma
- bleeding disorder
- conditions related to genital scarring (Peyronie’s disease); priapism
- predisposition to hypertension, hypotension or dystonia
- stomach or duodenum ulcer
Eventual adverse events
Levitra Super Force can give side effects that range in their intensity from mild to moderate. They are:
- stomach upset
- dry mouth
Seek medical assistance without delay if you experience the symptoms from the list below:
- irregular heartbeat rate
- swelling of the face, lips, tongue
- pain in the chest or arm
- obstructed breathing
- suicidal thoughts
- severe depression
Interactions to avoid
Keep your prescriber informed about the medications you are currently taking. Levitra Super Force is not compatible with the drugs from the following groups:
- drugs against high blood pressure
- drugs against chest pain and heart conditions
- drugs against BPH
- drugs against AIDS / HIV
- drugs against fungal infections
- drugs against blood clotting
- drugs metabolized by CYP3A4
- grapefruit / grapefruit juice
Never take more than one recommended dose (one tablet) of Levitra Super Force during 24 hours. Violating the safe intake rules may result in increased toxicity of the drug and overdose symptoms. If this happens, contact your doctor or any other accessible healthcare specialist as soon as possible.
Does not apply to Levitra Super Force. Take a pill as soon as you remember to and wait for an hour for the natural reaction towards sexual stimulation to occur.
The package with Levitra Super Force should be stored in a cool dry place where children and pets cannot have access to it.
The drug should not be used in excessive doses or after the expiry date. If you suspect that you have been exposed to the elevated dose of Levitra Super Force, report to the nearest ER or poison control center immediately.