Cialis Professional

What is it used for?

Cialis Professional (tadalafil citrate) is an oral drug used to restore the erectile potential in male patients. The drug is taken as needed, before engaging in sexual activity, to continue producing the effects during the ensuing 24 hours. Cialis Professional has displayed high level of efficacy in patients with mild, moderate and severe degree of erectile dysfunction.

Cialis Professional contains tadalafil citrate, and by ordering the drug from our website you acknowledge that you have familiarized yourself with the information on how to use the drug, choose the correct dose, and what to do in case of unwanted effects of Cialis Professional. We recommend that you consult your healthcare provider before starting Cialis Professional therapy and / or in case of developing adverse reactions during the treatment course.

Drug mechanism and characteristics

Cialis Professional falls into the class of drugs used orally for correction of damaged caused by erectile dysfunction (ED). Tadalafil citrate contained in Cialis Professional is a vasoactive substance that acts as a cardiovascular relaxant, making the blood vessels in the smooth muscles of the penis expand. This makes the blood flow towards the penis.

This mechanism is possible thanks to inhibition of phosphodiesterase type 5, hence the name of the drug class tadalafil belongs to – PDE5 inhibitors. Binding PDE5 triggers the release of nitric oxide, which in its turn prevents the conversion of cyclic guanosine monophosphate (cGMP) to guanosine triphosphate (GTP). The substance cGMP is a precursor of healthy erection, but sexual stimulation is required for it to be released in response to NO signal from the brain.

Thus, Cialis Professional will not give you a spontaneous erection or an increase in libido, but will only act as a erectogenic agent against a background of a clinically diagnosed ED.

Drug dosing and applications

Cialis Professional is available in doses tadalafil 20mg and tadalafil 40mg. The dose recommended for each patient individually is established by a healthcare provider based on a number of factors and necessarily after a physical examination and possibly a number of laboratory tests.

As a general rule, patients are started on lower doses of tadalafil, so if you are a beginner, you will be either recommended to take another tadalafil-containing drug, or half a tablet of Cialis Professional. The dose will then be increased if the effects are as meaningful as expected, but only if approved by prescriber.

The maximal dose of Cialis Professional is only administered to otherwise healthy individuals without renal or hepatic issues.

Take a pill of Cialis Professional whole, with or without meals, following with half to full glass of water. The effects of the drug will be unaffected by simultaneous intake of food or alcohol, which is one of the drug’s benefits as compared to other medications in its class. Taking Cialis Professional brings down the risk of side effects.

The drug starts acting 30 minutes after intake, but the window of responsiveness may vary from patient to patient. Cialis Professional duration of effects is 36 hours.

Interactions with other medications

Cialis Professional can interact dangerously with drugs from the following groups:

  • antihypertensive drugs
  • antifungal drugs
  • antiretroviral drugs
  • drugs and substances metabolized by CYP3A4 enzyme, including grapefruit and grapefruit juice.

Cautious use

Cialis Professional should be used with caution by individuals with creatinine clearance below 50 mL/min and liver insufficiency. For the same reason, caution should be exercised when appointing the drug in geriatric populations: Cialis Professional contains elevated doses of tadalafil, and people over 65 tend to have decreased creatinine clearance, which may lead to toxic levels of tadalafil in plasma.

Contraindications for the use of Cialis Professional

Cialis Professional should not be used against the background of the following conditions:

  • congestive heart failure, heart disease, stroke, angina pectoris, and associated conditions;
  • ulcerative diseases of GIT;
  • severe renal or hepatic insufficiency;
  • degenerative disease of the eye, eye retina, NAION, glaucoma;
  • Peyronie’s disease, priapism;
  • diseases of blood cells and vessels;
  • uncontrolled blood pressure;
  • sensitivity towards drug components.

Possible unwanted reactions

Cialis Professional can cause adverse reactions, even if used correctly. They occur in a fraction of patients, are fleeting and disappear in the advanced stages of therapy. They are:

  • Back pain
  • Nasal congestion / discharge
  • Headache
  • Stomach upset
  • Hives
  • Nausea

Cialis Professional may cause severe side effects that require immediate medical attention:

  • Irregular heartbeat rate
  • Difficulty breathing
  • Pain in the chest and / or arm
  • Swelling of the lips, tongue, face
  • Fainting
  • Vomiting
  • Migraine

Overdose management

Taking excessive doses of Cialis Professional can result in increased toxicity of the drug. Adhering to medication instructions is important to avoid overdosing on tadalafil. The overdose symptoms will manifest themselves as severe Cialis Professional side effects. Seek your doctor’s help if you experience any of them.

Missed dose instructions

Missed dose rules do not apply to Cialis Professional outside of the classical recommendations to not double-dose when you have forgotten to take the drug timely prior to engaging in anticipated sexual activity.

Storage

Cialis Professional should be stored at room temperature in a cool dry place.

Toxicity

Cialis Professional can build up to toxic levels in patients with decreased creatinine clearance, in combinations with incompatible drugs, in increased doses or when taken without regard to medication instructions.