Cialis Oral Jelly

What is it used for?

Cialis Oral Jelly (tadalafil citrate) is administered to individuals with compromised erectile ability to restore the sexual function for the period of 36 hours. Cialis Oral Jelly starts acting 20 minutes following dosing; during its effect duration, user can easily achieve hard and controllable erections with minimal sexual stimulation.

Cialis Oral Jelly contains tadalafil citrate as its active component. By purchasing Cialis Oral Jelly, you confirm that you are aware about the nature of this active substance, its dosing instructions, as well as the instructions for its safe use and management of eventual unwanted effects. Cialis Oral Jelly requires medical recommendations. In the event of side effects, it is recommended to seek medical help from your GP or any other healthcare provider.

Drug mechanism of action

Cialis Oral Jelly (tadalafil citrate) is an orally administered inhibitor of phosphodiesterase type 5 produced in the form of gel contained in a monodose sachet. Tadalafil produces a powerful vasodilatory effect by binding PDE5 and releasing nitric oxide (NO). The healthy erectile mechanism starts by the brain sending the signal to the smooth muscles of the penis to relax and absorb maximal amount of blood, and NO molecules are the “messengers”. In response, cyclic guanosine monophosphate (cGMP) is accumulated in the erectile bodies of the penis, and the blood flows into them to remain there until the climaxing.

In men with ED, this process is disrupted at the level where PDE5 interferes with the production of cGMP, catalyzing its conversion to guanosine triphosphate (GTP). Cialis Oral Jelly inhibits PDE5 and restores the healthy erectile mechanism for 36 hours, but sexual stimulation is required for the drug’s action to manifest itself. Cialis Oral Jelly does not affect sexual desire.

Recommended doses and drug use

Cialis Oral Jelly is produced in the dose of 20mg of peroral gel contained in a sachet. The dose of 20mg is the maximal recommended dose of tadalafil, while there exist drugs with lower content of tadalafil more suitable for initial therapy in the beginners. If you have experience with other tadalafil medications and there are no particular side effects, comorbidities or other circumstances to consider, your prescriber can approve Cialis Oral Jelly 20mg for you.

Take the content of one Cialis Oral Jelly sachet 20 minutes before the anticipated sexual activity. The drug can be taken on an empty stomach or after a meal. Postprandial intake of Cialis Oral Jelly decreases the incidence of side effects.

Drug interactions to avoid

Cialis Oral Jelly should not be taken with the following groups of drugs:

  • drugs against high blood pressure
  • drugs against pain in the chest / heart conditions / alpha-blockers
  • drugs against prostate conditions
  • drugs against fungal infections
  • drugs against seizures
  • drugs against bacterial infections
  • drugs against retroviruses
  • drugs metabolized by CYP3A4 enzyme

Cautious use

If your doctor establishes that sexual activity is too strenuous for your heart and can pose a risk for your health and life, you should not take Cialis Oral Jelly.

Patients with decreased creatinine clearance should not take Cialis Oral Jelly; drugs with lower doses of tadalafil are recommended. The classic Cialis pills have more diversified lineage of doses.

Do not take Cialis Oral Jelly after consuming grapefruit or grapefruit juice.

Contraindications for the use of drug

Cialis Oral Jelly should not be taken in the presence of the following health conditions:

  • heart disease
  • stroke within the past half a year
  • diseases of blood vessels / cells
  • diseases of eye retina, eye nerve, glaucoma
  • ulcerative diseases of GIT
  • Peyronie’s disease
  • priapism
  • sensitivity towards tadalafil or lactose
  • uncontrolled hypertension / hypotension
  • kidney insufficiency
  • liver insufficiency

Possible side effects

Cialis Oral Jelly may trigger the onset of the following side effects:

  • Back pain
  • Headache
  • Rhinitis
  • Nausea
  • Facial flushing
  • Upset stomach
  • Skin hives
  • Visual disturbances
  • Ringing in the ears

Developing one or more of the following side effects is grounds for seeking immediate medical help and discontinuing the use of the drug:

  • compromised breathing
  • palpitations
  • swelling of the mouth, face
  • vomiting
  • fainting
  • severe headache
  • angina
  • seizures

Overdose signs and management

Cialis Oral Jelly overdose will manifest itself as severe side effects from the list cited in the section above. It is important to follow the instructions given in the medication insert and shared by your prescriber in order to avoid overdose symptoms. If you think you have taken an elevated dose of tadalafil, call poison control center or your prescriber.

Storage

Cialis Oral Jelly should be stored in a cool dry place away from children and pets.

Toxicity

The toxic levels of Cialis Oral Jelly in blood plasma can be reached if the drug is taken in doses that exceed the recommended. Keep in mind that the “recommended dose” is something that is established individually for every patient, and those with compromised kidney function will reach the toxic level faster than healthy individuals. In the event of overdose, seek immediate medical assistance.